Favorable treatment for rare case tumor in oral cavity: A whartin’s tumor review article

Nanda Rachmad Putra Gofur; Aisyah Rachmadani Putri Gofur; Soesilaningtyas; Rizki Nur Rachman Putra Gofur; Mega Kahdina; Hernalia Martadila Putri

Favorable treatment for rare case tumor in oral cavity: A whartin’s tumor review article

Authors
Nanda Rachmad Putra Gofur, Aisyah Rachmadani Putri Gofur, Soesilaningtyas, Rizki Nur Rachman Putra Gofur, Mega Kahdina, Hernalia Martadila Putri

Abstract
Introduction: Warthin's tumor is a benign tumor of the salivary glands, especially in the parotid gland, usually cystic, 10% of all tumors are usually bilateral. Meanwhile, based on the histological image, the tumor is formed by a wide acinus with a papillary-cystic appearance. The epithelium is similar to the salivary ducts which are attached by dense lymphoid tissue that is visible in the lymphoid follicles. According to the Hamburg Salivary Gland Registry, the overall incidence of salivary gland tumors is 5 per 100,000 with an estimated 65% of these tumors being benign. Warthin's tumor ranks second after pleomorphic adenoma of the parotid gland, 90% of cases occur in the superficial lobe of the parotid gland and rarely in the deeper lobe (10%). And Warthin's tumors account for about 15% of all epithelial tumors of the parotid gland.

Discussion: Definitive diagnosis requires a tissue sample. Fine needle aspiration (FNA) has played a larger role in recent years. In general, FNA has good overall accuracy for diagnosing salivary gland tumors (87% to 97%), and has been widely used for the diagnosis of Warthin's tumor. The main treatment for salivary gland tumors is surgery. Radiotherapy as postoperative adjuvant therapy is given only as indicated, or given to inoperable salivary gland carcinoma. Chemotherapy is only given as an adjuvant, although it is still under study, and the results are not satisfactory.

Conclusion: The prognosis for salivary gland cancer depends on staging, histology, type of cancer, patient age, and adequacy of evidence from surgical removal. The most important prognostic factor is cancer staging. Furthermore, the most important factor is the histologic grade of the cancer.

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