International Journal of Dental Sciences

Authors
Joseph Johny, Sinitha Sreedhar, Jaseela C R, Sruthy S, Agna Ratheesh

Abstract
Oral cancers constitute approximately 2% of all cancers. About 96% of oral cancers are carcinomas and remaining 4% are sarcomas .majority of oral carcinomas are squamous cell carcinomas. Its estimate d that 9 out of every 10 oral malignancies is oral squamous cell carcinomas. It is a disease of increasing age with 95% of the patients older than 40 years of age. OSCC has high recurrence rate and poor prognosis so exploring new therapeutic strategies has become an urgent priority. Exosomes are extracellular vesicles, released from different tissues in a living individual. They can be released from both the normal and diseased cells. Exosomes have been associated with tumorogenesis of OSCC, promote the proliferation, colonization and metastasis of OSCC. They play an important role in the diagnosis, prognosis, and therapeutic aspect of a disease.