The nasolabial flap is a common flap used to repair nasal, labial, and intraoral defects.The use of inferiorly based nasolabial flaps in the treatment of oral submucous fibrosis is proposed in this article (OSMF).The use of a nasolabial flap in the treatment of a patient with clinically proven OSMF was investigated. The patient had an interincisal opening of less than 15 mm, which was treated by bilateral fibrous band release, intraoperative interincisal distance measurement (more than 40 mm following band release), and inferiorly based nasolabial flap filling the deficiencies. Patients received postoperative physiotherapy and were monitored for two years. There were no signs of infection, dehiscence, or necrosis after the flap healed.