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International Journal of
Dental Sciences
ARCHIVES
VOL. 6, ISSUE 1 (2024)
Evaluation of the effect of mangosteen peel extract (Garcinia Mangostana l.) against the wound healing process after tooth extraction
Authors
Zhao Yimi
Abstract
Tooth extraction can lead to the opening of a wound on the alveolar bone inside the oral cavity. The peel of mangosteen fruit (Garcinia mangostana L.) contains various compounds such as saponins, alkaloids, flavonoids, triterpenoids, tannins, and polyphenols. Hence, mangosteen peel has pharmacological effects, including anti-inflammatory, antioxidant, antidiabetic, and antibacterial. This study aimed to analyze the impact of ethanol extract of mangosteen peel (Garcinia mangostana L.) with a concentration of 50% and 100% on wound healing time after tooth extraction in the Wistar strain male rats. The test animal population consisted of 32 male Wistar rats. Data was analyzed using the SPSS 21 program with a nonparametric Chi-Square Test and a Sig value (p<0.05). The results showed a significant relationship between the number of fibroblast tissues per field of view in Wistar rats after tooth extraction with the administration of mangosteen peel extract (Garcinia mangostana L.) concentrations of 50% and 100%, p = 0.002 (p < 0.05). In conclusion, mangosteen peel extract (Garcinia mangostana L.) at 50% and 100% effectively accelerated wound healing time after tooth extraction in Wistar rats.
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Pages:6-8
How to cite this article:
Zhao Yimi "Evaluation of the effect of mangosteen peel extract (Garcinia Mangostana l.) against the wound healing process after tooth extraction". International Journal of Dental Sciences, Vol 6, Issue 1, 2024, Pages 6-8
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