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VOL. 6, ISSUE 1 (2024)
Evaluation of the effect of mangosteen peel extract (Garcinia Mangostana l.) against the wound healing process after tooth extraction
Authors
Zhao Yimi
Abstract
Tooth extraction can lead to the opening of a wound on the alveolar
bone inside the oral cavity. The peel of mangosteen fruit (Garcinia mangostana
L.) contains various compounds such as saponins, alkaloids, flavonoids,
triterpenoids, tannins, and polyphenols. Hence, mangosteen peel has
pharmacological effects, including anti-inflammatory, antioxidant,
antidiabetic, and antibacterial. This study aimed to analyze the impact of
ethanol extract of mangosteen peel (Garcinia mangostana L.) with a
concentration of 50% and 100% on wound healing time after tooth extraction in the
Wistar strain male rats. The test animal population consisted of 32 male Wistar
rats. Data was analyzed using the SPSS 21 program with a nonparametric
Chi-Square Test and a Sig value (p<0.05). The results showed a significant
relationship between the number of fibroblast tissues per field of view in
Wistar rats after tooth extraction with the administration of mangosteen peel
extract (Garcinia mangostana L.) concentrations of 50% and 100%, p = 0.002 (p
< 0.05). In conclusion, mangosteen peel extract (Garcinia mangostana L.) at
50% and 100% effectively accelerated wound healing time after tooth extraction
in Wistar rats.
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Pages:6-8
How to cite this article:
Zhao Yimi "Evaluation of the effect of mangosteen peel extract (Garcinia Mangostana l.) against the wound healing process after tooth extraction". International Journal of Dental Sciences, Vol 6, Issue 1, 2024, Pages 6-8
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