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VOL. 6, ISSUE 1 (2024)
Evaluation of the effect of using turmeric ethanol extract (Curcuma Longa) in healing wounds after tooth extraction
Authors
Li Jinling
Abstract
Turmeric (Curcuma longa Linn or Curcuma
domestica Val) has been known by the public as a source of diverse benefits,
including anti-inflammatory, anticancer, antioxidant, antiulcer, and
antibacterial. This study aimed to evaluate the effectiveness of turmeric
extract (Curcuma longa) with concentrations of 40% and 80% in accelerating the
wound healing process after tooth extraction in Wistar rats. This laboratory
experimental study used a randomized design complete with a post-test-only
control group design pattern. A total of 32 physically healthy male Wistar
rats, aged 2-3 months, weighing 200-250 grams, were used as research subjects. Federer's
formula determines the sample size, namely: (t - 1) (r - 1) ≥ 15, and the
minimum number of samples for each treatment is 16 mice. The results showed
that there was a significant relationship between the number of fibroblast
tissues per field of view in Wistar rats after tooth extraction with turmeric
extract (Curcuma Longa) concentration of 40% and turmeric extract (Curcuma
longa) concentration of 80%, with a value of p = 0.001 (p < 0.05). It can be
concluded that turmeric extract (Curcuma longa) at concentrations of 40% and
80% effectively accelerates the healing time of wounds after tooth extraction
in Wistar rats. In addition, turmeric extract (Curcuma longa) at a
concentration of 80% proved to be more effective than turmeric extract (Curcuma
longa) 40% in accelerating the wound healing process, possibly due to the
flavonoid content in turmeric extract (Curcuma longa) 80% which helps increase
the speed of wound healing compared to turmeric extract (Curcuma longa) 40%.
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Pages:9-12
How to cite this article:
Li Jinling "Evaluation of the effect of using turmeric ethanol extract (Curcuma Longa) in healing wounds after tooth extraction". International Journal of Dental Sciences, Vol 6, Issue 1, 2024, Pages 9-12
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