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VOL. 6, ISSUE 1 (2024)
Review of the effectiveness of garlic ethanol extract (Allium Sativum) on the acceleration of post-tooth extraction wound healing in wistar rats
Authors
Liang Ming
Abstract
One of the natural ingredients that can be used in the treatment of
wounds is garlic because it contains active compounds that can suppress the
growth of microorganisms in the inflammatory phase and accelerate tissue
regeneration in the remodeling phase. This study aimed to analyze the
effectiveness of garlic extract (Allium sativum) 25% and 25% in accelerating
wound healing time after tooth extraction in Wistar rats. This laboratory
experimental study uses a randomized design complete with a post-test-only
control group design pattern. The experimental animals were 32 Wistar rats,
males, physically healthy, aged 2-3 months, and weighing 200-250 grams. The treatment
was divided into two groups, namely 16 rats treated with garlic extract (Allium
sativum) 25% and 16 rats treated with garlic extract (Allium sativum) 25%, to
compare the acceleration of wound healing after tooth extraction. Data analysis
using the SPSS 21 program with a non-parametric Chi-Square Test after the test
showed that (p<0.05) means significant differences between groups. The
results of data analysis showed a significant relationship between the number
of fibroblast tissues per field of view in Wistar rats after tooth extraction
with the administration of Garlic Extract (Allium sativum) concentration of 25%
and Garlic Extract (Allium sativum) concentration of 25% with a value of p =
0.008 (p < 0.05). In conclusion, garlic extract (Allium sativum)
concentrations of 25% and 25% effectively accelerated wound healing time after
tooth extraction of Wistar rats. Garlic extract (Allium sativum) is 25% more
effective than garlic extract (Allium sativum) 25% in accelerating wound
healing time after tooth extraction of Wistar rats because the flavonoid
content in garlic extract (Allium sativum) 25% which helps accelerate wound
healing is higher than garlic extract (Allium sativum) 25%.
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Pages:17-21
How to cite this article:
Liang Ming "Review of the effectiveness of garlic ethanol extract (Allium Sativum) on the acceleration of post-tooth extraction wound healing in wistar rats". International Journal of Dental Sciences, Vol 6, Issue 1, 2024, Pages 17-21
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