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VOL. 6, ISSUE 1 (2024)
Evaluation of the effect of areca nut seed extract in facilitating wound healing after tooth extraction in wistar rats
Authors
Yuan Xinming
Abstract
One of the plants
commonly used by the community for wound healing is the betel nut (Areca
catechu L.), distributed widely throughout Indonesia. Betel nut (Areca catechu
L.) contains phytochemical compounds beneficial for wound healing, such as
antioxidants, anti-inflammatory, and antibacterial agents. This study aims to
evaluate the effectiveness of betel nut (Areca catechu L.) seed extract in
accelerating the healing process after tooth extraction. This laboratory
experimental research used a completely random design with a post-test-only control
group design. Thirty-two healthy male Wistar rats, aged 2-3 months and weighing
200-250 grams, were used as research subjects. The rats were divided into two
groups: 16 rats received treatment with 60% betel nut (Areca catechu L.) fruit
extract, and 16 rats received treatment with 120% betel nut (Areca catechu L.)
fruit extract to compare the acceleration of wound healing after tooth
extraction. Data analysis was performed using SPSS 21, and the study adopted a
pure experimental method with a non-parametric Chi-Square Test. After the test,
the results showed that (p < 0.05), indicating a significant difference
between the groups. The study results demonstrated a significant relationship
between the number of fibroblast tissues per field of view in Wistar rats after
tooth extraction with the administration of betel nut (Areca catechu L.) fruit
extract at concentrations of 60% and 120%, with a p-value of 0.001 (p <
0.05).
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Pages:22-25
How to cite this article:
Yuan Xinming "Evaluation of the effect of areca nut seed extract in facilitating wound healing after tooth extraction in wistar rats". International Journal of Dental Sciences, Vol 6, Issue 1, 2024, Pages 22-25
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