In modern clinical practice, digital pathology plays a crucial role and is increasingly a technological requirement in the laboratory environment. The advent of whole slide imaging, the availability of faster networks, and cheaper storage solutions make it easier for pathologists to manage digital slide images and share them for clinical use.

In this review, we seek to demonstrate the deep learning systems: their potential to function on par with humans in classifying images into diagnostic categories; some of the AI software used in evaluating histopathology images; the significance of AI in evaluating oral mucosal lesions using dermoscopy; challenges and opportunities of AI in digital pathology.