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International Journal of
Dental Sciences
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VOL. 7, ISSUE 2 (2025)
A compendium on remineralizing agents in preventive dentistry
Authors
Shreya BS, Ashwini S Colaco, Sharanya V Rao
Abstract

Dental caries is a complex, cyclical process involving repeated phases of demineralization and remineralization. Remineralization serves as the body’s natural repair process, in which calcium and phosphate ions from oral fluid are redeposited into the hydroxyapatite (HAP) crystal structure of enamel. Minimal intervention is a key phrase in today's dental practice. Minimal Intervention Dentistry (MID) emphasizes preserving natural tooth structure through preventive care, early detection, and minimally invasive treatments. This approach focuses on managing dental caries at its earliest stages, aiming to reduce the need for extensive restorative procedures. The process of tooth remineralization has been extensively researched, leading to innovative technologies that promote enamel repair and prevent demineralization. Various remineralizing agents have been utilized to restore enamel and treat white spot lesions (WSLs). Fluoride has formed the mainstay of enamel remineralization for many decades. It is known to control caries predominantly through its topical effect inhibiting demineralization by forming fluorapatite on the enamel surface. 

 Recent research has moved towards biomimetic approaches. The term “Biomimetics” is derived from the Latin words “bios” which means life and “mimesis” which means to copy or mimic. Biomimetic remineralization has emerged as a transformative approach in dental research, aiming to restore the structural and functional integrity of demineralized enamel by emulating natural mineralization processes. This article reviews the progress in dental remineralization strategies and highlights the essential qualities of an effective remineralizing material.
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Pages:38-43
How to cite this article:
Shreya BS, Ashwini S Colaco, Sharanya V Rao "A compendium on remineralizing agents in preventive dentistry". International Journal of Dental Sciences, Vol 7, Issue 2, 2025, Pages 38-43
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