Background and objectives: To assess and compare the influence of calcium hydroxide (CH) and triple antibiotic paste (TAP) on the push-out bond strength of AH Plus BC sealer at the coronal, middle, and apical thirds of the root canal.

Materials and methods: Altogether of 45 extracted, single-rooted premolar teeth were selected, decoronated, and instrumented using the ProTaper rotary file system up to size F3. The samples were distributed randomly into three groups (n=15) in accordance with the intracanal medicament applied: Group A — no medicament, Group B — calcium hydroxide, and Group C — triple antibiotic paste. The medicaments remained in the canals for three weeks. Following this period, canals were irrigated sequentially with 10 mL of 17% EDTA, 10 mL of 2.5% sodium hypochlorite, and a final rinse with 5 mL distilled water. Canal spaces were subsequently obturated using AH Plus BC sealer in combination with a single-cone gutta-percha technique. Post-obturation, horizontal sections of the roots were made to create 2 mm thick slices from the coronal, middle, and apical thirds. The bond strength between the root canal dentin and the sealer was evaluated using a universal testing machine through a push-out bond strength test.

Result: Variation in intracanal medicaments notably affected the push-out bond strength of AH Plus BC sealer. Bond strength was nearly twice as high following the application of triple antibiotic paste (TAP) compared to calcium hydroxide (CH), and these results were independent of the position along the canal.