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VOL. 7, ISSUE 4 (2025)
The scope and prospects of Lugol's Iodine vital staining in diagnosis of oral lesions
Authors
Dr. V Shanthi, Dr. S Arulraja, Dr. R Kanmani, Dr. T Maheswaran, Dr. N Preethi, Dr. G Jisha
Abstract
Lugol's iodine vital staining represents a cost-effective adjunctive
diagnostic tool for detecting oral epithelial dysplasia and squamous cell
carcinoma. This technique exploits the differential glycogen content between
normal and dysplastic epithelium, enabling the visualization of lesion margins
that may be clinically unremarkable. Current evidence demonstrates high
sensitivity for malignancy detection and significant utility in surgical margin
delineation, although the specificity remains moderate. This review examines
the mechanistic basis, diagnostic performance, clinical applications, and
future directions of Lugol's iodine staining in contemporary oral medicine
practice.
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Pages:137-138
How to cite this article:
Dr. V Shanthi, Dr. S Arulraja, Dr. R Kanmani, Dr. T Maheswaran, Dr. N Preethi, Dr. G Jisha "The scope and prospects of Lugol's Iodine vital staining in diagnosis of oral lesions". International Journal of Dental Sciences, Vol 7, Issue 4, 2025, Pages 137-138
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