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VOL. 8, ISSUE 2 (2026)
A scoping review of plasma cell and eosinophil rich lesions of the oral cavity
Authors
Santhiya A, Sivagurunathan N, Sowmya R, Sreeja S Nair, Sri Kiruttika Devi S, Dr. Kavitha Muthu
Abstract
This review aims to summarize the main
features, potential causes, and diagnostic methods of plasma cell- and
eosinophil-rich oral lesions, and to provide information on their clinical
manifestations, pathogenesis, and treatment strategies. A comprehensive review
of the literature was performed, examining studies of oral lesions
characterized by significant plasma cell and eosinophil infiltration. Articles
were analyzed for common conditions associated with these cell types,
histopathological findings, clinical manifestations, and treatment methods.
Plasma cell- and eosinophil-rich oral lesions are commonly associated with
conditions such as plasma cell gingivitis, eosinophilic granulomatosis, oral
manifestations of systemic diseases such as eosinophilic granulomatosis with
polyangiitis, and allergic reactions such as eosinophilic stomatitis.
Histopathological examination usually reveals an inflammatory infiltrate
dominated by plasma cells and eosinophils, with different patterns depending on
the underlying cause. Clinically, these lesions often present as painful,
swollen, or ulcerated areas of the oral mucosa, requiring careful diagnostic
evaluation.
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Pages:83-88
How to cite this article:
Santhiya A, Sivagurunathan N, Sowmya R, Sreeja S Nair, Sri Kiruttika Devi S, Dr. Kavitha Muthu "A scoping review of plasma cell and eosinophil rich lesions of the oral cavity". International Journal of Dental Sciences, Vol 8, Issue 2, 2026, Pages 83-88
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