Background: Children with cerebral palsy (CP) frequently experience compromised oral hygiene due to impaired neuromuscular coordination, making caregiver-assisted tooth brushing essential. The comparative efficacy of angled and U-shaped toothbrushes for plaque removal in this population remains poorly characterized.

Aim: To evaluate and compare the plaque removal efficacy of caregiver-administered brushing using an angled toothbrush versus a U-shaped toothbrush among children with cerebral palsy.

Materials and Methods: A randomized controlled trial will be conducted over one month among 20 children (aged 6-15 years) with cerebral palsy attending a special school in Sullia, Karnataka. Following informed consent, participants will be randomly allocated into two groups of 10. Group I caregivers will brush the child's teeth using a U-shaped toothbrush, and Group II caregivers will use an angled toothbrush with a scrub technique, each for 2 minutes, twice daily for 21 days. Plaque accumulation will be assessed at baseline, day 7, and day 21 using the Turesky Modification of the Quigley-Hein Plaque Index. Data will be analyzed using SPSS software, with unpaired t-tests for intergroup comparisons and ANOVA for intragroup comparisons across time points; p < 0.05 will be considered statistically significant.

Results: Both groups showed a statistically significant reduction in plaque scores from baseline to day 21 (p < 0.05). However, the U-shaped toothbrush group demonstrated a significantly greater reduction in plaque accumulation at both day 7 and day 21 compared with the angled toothbrush group (p < 0.05).