Introduction: The present century in medical sector is flooded with various allopathic options for treatment of diseases. It is indeed a boon but have introduced synthetic chemicals in human body. It has many side effects and microbes too are developing resistance to such drugs. Antimicrobial activity of clove oil is attributed by disturbing the cell wall and membrane cell lysis, leakage of cellular contents and inhibition of proton motive force. The aim of this study was to check efficacy of clove extract against streptococcus mutans.

Methodology: The efficacy of clove will be assessed by agar well diffusion method. Results: clove extract was effective at 100% concentration.