Background: Periodontitis is a chronic inflammatory disease caused by bacterial infection of the gums and supporting structures of the teeth. Localized delivery of antimicrobial agents into periodontal pockets is a proven strategy to reduce bacterial load and promote healing. The conventional Perio-Chip, containing chlorhexidine gluconate in a biodegradable matrix, has been used for this purpose. However, its clinical utility is limited by a short release duration (7 days), technique-sensitive placement, higher cost, and occasional patient discomfort or allergic reactions.

Aim: To develop a novel black chip with enhanced therapeutic properties for the treatment of periodontitis, offering extended drug release, improved handling, and greater shelf stability, thereby overcoming the limitations of existing products.

Materials and Methods: The black chip is formulated using a biodegradable glycolide-lactic acid co-polymer matrix, embedded with chlorhexidine gluconate as the active antimicrobial agent.The chip measures approximately 4 mm × 5 mm × 0.5 mm, similar to the conventional Perio-Chip.Flexible structure for easier and more precise placement into periodontal pocketsModified polymer blend to allow sustained release over 14 daysIncorporation of stabilizing excipients to improve shelf lifeApplication Method: The chip is inserted into the periodontal pocket using standard dental instruments, with minimal discomfort to the patient.