Objective: To evaluate the bond strength of polymethyl methacrylate (PMMA) when cemented using two different strategies: light-cured resin cement and preheated composite resin.

Method: Sixteen PMMA sheets (n = 8 per group) were prepared and standardized in size. The samples were randomly divided into two groups: (1) cementation with light-curing resin cement and (2) cementation with composite resin preheated to 55–60 °C. Each group was further divided into two subgroups: 1) Sandblasting: the PMMA surfaces were sandblasted with 50 μm aluminum oxide for 5 seconds; and 2) Phosphoric acid: phosphoric acid was applied to the PMMA surface for 15 seconds. Subsequently, 4 resin microtubes were cemented onto each sheet; these were fabricated from Tygon tubing and composite resin, then light-cured using a high-power Valo Grand LED lamp. After 24 hours of storage in distilled water, the specimens were subjected to a micro-shear test on a universal testing machine, with values recorded in MPa at a speed of 0.5 mm/min. Results: Based on this study, it is concluded that the protocol consisting of resin cement combined with PMMA sandblasting is established as the safest, most effective, and most predictable option for indirect restorations.